Launching a Health Report on Cutaneous Squamous Cell Carcinoma
Team Genomes are excited to announce the launch of a Cutaneous Squamous Cell Carcinoma Health report on our infrastructure, providing our vault holders with crucial insight into their genome.
Cutaneous Squamous Cell Carcinoma (cSCC) is a common type of skin cancer that develops in the squamous cells of the skin’s outer layer. It is the second most common non-melanoma skin cancer, following basal cell carcinoma, and is primarily linked to ultraviolet exposure.
Squamous cell carcinoma may present as scaly red patches, open sores, rough or thickened skin, wart-like growths, or raised bumps with a central depression. These lesions can sometimes crust over, itch, or bleed, and are most often found on sun-exposed areas of the body. However, SCCs can also develop in less exposed regions, such as the genitals.
Although the primark risk factor is exposure to ultraviolet radiation, genetics also play a role in the condition. If you have a family history of skin cancer, this may increase your susceptibility to the disease. As well as family history, certain genetic conditions can increase your susceptibility. For example, individuals with xeroderma pigmentosum have a risk of developing non-melanoma skin cancer that is approximately 10,000 times higher than those who do not suffer from the condition.
Although most SCCs can be treated effectively, if left untreated, they can become dangerous, or even life-threatening. These lesions may invade deeper layers of the skin and spread to other parts of the body, increasing the risk of severe complications.
If you wish to learn more about the condition, you can read here.
Why are we doing this?
With these reports it is our goal to provide our users with crucial insights about their health using genomic data so they can better understand who they are and act effectively to live a long, healthy and happy life.
One of our other aims at Genomes is to safely and equitably contribute to scientific research that benefits the future health of all of us. We are very happy to be working towards this through our health reports. We invite you to embark on this exciting journey with us!
IMPORTANT NOTE: The information provided in our report is genotypic, and is not intended as medical advice or as a diagnosis. If you have any concerns based on the results, we strongly recommend consulting a medical professional who can provide the appropriate guidance and support.
How the report works
Our reports make use of Genome Wide Association studies (GWAS) which compare affected individuals against unaffected individuals in order to identify susceptibility genes. The data from GWAS studies allow us to calculate a polygenic risk score based on your sequenced genome.
The GWAS studies work by examining Single Nucleotide Polymorphisms (SNPs), which are a single base pair change in your DNA sequence. These act as genetic markers, which can be seen in affected individuals and associated with nearby genes. Once there has been association made this can be further examined by looking on online databases, allowing the confirmation of it being a risk or susceptibility gene.
The test will show you a polygenic risk score, which allows you to see the risk of developing the disease based on your genetic variations. No raw data will ever leave your vault, with the reports being generated within your web account.
To run your test and get your personalised results, head over to your dashboard at Genomes.io.
As always, feel free to connect with us via info@genomes.io should you have any further questions. We are happy to help wherever we can.
If you want to earn rewards for simply uploading your DNA, Genomes.io’s new point system let’s you unlock tokens just by participating.
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